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Interestingly, the poly(rC)-binding protein (PCBP)1 and PCBP2 were found upregulated both at the gene (day 50, in culture) and protein (day 100, in culture) level in AD brain organoids

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the subsequently released iron ions are reduced to the ferrous form by STEAP3, a six-transmembrane reductase selectively enriched in prostate epithelium ( 2+ is imported into the labile iron pool (LIP) in the cytoplasm via DMT1 or its functional partner ZIP14 (Nemeth and Ganz, 2021)